The SAS System                                                                 1

Parametric Log-normal Model for First Gap Time
----------------------------------------------

The LIFEREG Procedure

            Model Information

Data Set                    WORK.RHDNASE1
Dependent Variable             Log(gtime)
Censoring Variable                 status
Censoring Value(s)                      0
Number of Observations                645
Noncensored Values                    243
Right Censored Values                 402
Left Censored Values                    0
Interval Censored Values                0
Name of Distribution            Lognormal
Log Likelihood                -643.247526

Number of Observations Read         645
Number of Observations Used         645

Algorithm converged.                                                       

       Type III Analysis of Effects
 
                         Wald
Effect       DF    Chi-Square    Pr > ChiSq

trt           1        9.8417        0.0017
fevc          1       55.7974        <.0001

                    Analysis of Parameter Estimates
 
                          Standard   95% Confidence     Chi-
Parameter     DF Estimate    Error       Limits       Square Pr > ChiSq

Intercept      1   5.4030   0.1048   5.1975   5.6085 2655.71     <.0001
trt            1   0.4302   0.1371   0.1614   0.6990    9.84     0.0017
fevc           1   0.0217   0.0029   0.0160   0.0273   55.80     <.0001
Scale          1   1.4460   0.0740   1.3080   1.5985                   

^LThe SAS System                                                                 2

Parametric Log-normal Model for Second Gap Time
-----------------------------------------------

The LIFEREG Procedure

            Model Information

Data Set                    WORK.RHDNASE2
Dependent Variable             Log(gtime)
Censoring Variable                 status
Censoring Value(s)                      0
Number of Observations                227
Noncensored Values                     81
Right Censored Values                 146
Left Censored Values                    0
Interval Censored Values                0
Name of Distribution            Lognormal
Log Likelihood               -194.5121106

Number of Observations Read         227
Number of Observations Used         227

Algorithm converged.                                                       

       Type III Analysis of Effects
 
                         Wald
Effect       DF    Chi-Square    Pr > ChiSq

trt           1        1.1591        0.2817
fevc          1        0.9314        0.3345
lgtime1       1        9.9683        0.0016

                    Analysis of Parameter Estimates
 
                          Standard   95% Confidence     Chi-
Parameter     DF Estimate    Error       Limits       Square Pr > ChiSq

Intercept      1   3.2090   0.4867   2.2550   4.1629   43.47     <.0001
trt            1  -0.2266   0.2105  -0.6390   0.1859    1.16     0.2817
fevc           1  -0.0045   0.0047  -0.0138   0.0047    0.93     0.3345
lgtime1        1   0.4173   0.1322   0.1582   0.6764    9.97     0.0016
Scale          1   1.2283   0.1056   1.0379   1.4536